Top 25 U.S. hospitals by cardiovascular disease diagnoses 

Cardiovascular disease, also known as heart disease, refers to a group of disorders that affect the heart and blood vessels. According to the WHO, cardiovascular diseases are the leading cause of death globally.  

Which hospitals treat the most patients with cardiovascular diseases? 

Using data from the Definitive Healthcare ClaimsMx product, we analyzed hospitals by their total number of primary cardiovascular diagnoses for outpatient visits. The most reported heart disease-related ICD-10 codes in 2021 were I10 (essential primary hypertension), I2510 (atherosclerotic heart disease of native coronary artery without angina pectoris), I4891 (Unspecified atrial fibrillation), I509 (heart failure unspecified) and I639 (cerebral infarction, unspecified).  

The following list shows hospitals in order of cardiovascular primary diagnoses for 2021.  

Hospital City State Definitive ID # Primary Diagnoses
Cleveland Clinic Main Campus Cleveland OH 3120 1,149,519
Mount Sinai Medical Center (AKA the Mount Sinai Hospital) New York NY 2837 455,900
University Hospital Ann Arbor MI 2096 327,637
Wilmington Hospital (AKA Wilmington Health Center) Wilmington DE 550103 172,444
UTMB - Texas Department of Criminal Justice Hospital Galveston TX 1047339 162,478
CHI St Vincent Infirmary Little Rock AR 270 128,384
CHRISTUS Mother Frances Hospital - Tyler Tyler TX 4127 126,104
William P Clements Jr University Hospital (FKA UT Southwestern University Hospital - St Paul) Dallas TX 3923 120,820
OhioHealth Riverside Methodist Hospital Columbus OH 3144 114,253
IU Health Methodist Hospital Indianapolis IN 1365 104,662
Methodist Hospital San Antonio TX 3862 101,896
Pikeville Medical Center Pikeville KY 1713 101,857
St David’s Medical Center Austin TX 4158 99,014
Cleveland Clinic Florida Weston FL 776 98,081
Huntsville Hospital Huntsville AL 81 92,844
The University of Tennessee Medical Center Knoxville TN 3784 92,831
Lahey Hospital & Medical Center - Burlington (FKA Lahey Clinic Hospital) Burlington MA 1956 83,190
Northern Light Eastern Maine Medical Center Bangor ME 1862 82,538
Piedmont Atlanta Hospital (AKA Piedmont Hospital) Atlanta GA 998 78,713
University of Cincinnati Medical Center (FKA University Hospital) Cincinnati OH 3158 78,683
Saint Francis Hospital and Medical Center Hartford CT 723 77,107
Deborah Heart and Lung Center Browns Mills NJ 2647 76,774
Spectrum Health Butterworth Hospital Grand Rapids MI 2035 72,268
Baptist Health Louisville (FKA Baptist Hospital East) Louisville KY 1681 71,488
University of Michigan Health-West (FKA Metro Health Hospital) Wyoming MI 2034 70,938

Fig. 1 Data is from the Definitive Healthcare ClaimsMx product for calendar year 2021. Claims data is sourced from multiple medical claims clearinghouses in the United States and is updated monthly. Data is accurate as of August 2022. 

Cleveland Clinic Main Campus, located in Ohio, ranks at the top of our list with more than one million cardiovascular disease primary diagnoses in 2021. This facility has several hundred thousand more outpatient diagnoses for cardiovascular diseases than the remaining hospitals on our list. This may be because Ohio is one of the least heart healthy states in the U.S. Out of the 50 states, Ohio ranked sixth for the most heart disease deaths in 2020, according to mortality data tracked by the CDC. On the other hand, the Cleveland Clinic’s heart program is consistently named number one in the nation by publications like U.S. News & World Report.   

Many of the hospitals on this list, like Mount Sinai Medical Center in New York and University Hospital in Michigan rank highly on our top hospitals by total operating expenses. Cleveland Clinic Main Campus and IU Health Methodist Hospital in Indiana also feature on our list of the top 20 national surgical quality improvement program (NSQIP) hospitals.  

What is heart disease? 

Cardiovascular disease (CVD) affects a person’s heart or blood vessels. The World Heart Federation describes four main types of CVD: 

  • Coronary heart disease: This occurs when the heart’s blood supply is blocked or interrupted by fatty substances in the arteries. 
  • Stroke: A serious medical condition that can lead to brain damage and possibly death if blood flow to the brain is restricted or stopped.  
  • Peripheral arterial disease: This occurs when there is a blockage in the arteries of a person’s limbs. 
  • Aortic disease: A type of heart valve disease affecting the aorta, the largest blood vessel in the body.  

There are many symptoms of CVD that could indicate poor heart health. Some symptoms include chest discomfort, pain in the throat or jaw, swollen extremities, an irregular heartbeat, and more.  

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