Healthcare Insights
Largest pain management physician group practices
If you’re looking for sales opportunities in the pain management market, physician groups can be compelling targets. The largest pain management physician groups have access to broader networks of specialists—and greater needs for equipment, supplies, technology, and other solutions.
How many pain management physician group practices are there in the U.S.?
According to our database, there are more than 900 active pain management physician group practices in the U.S. Because each physician group may operate several different locations to provide physicians access to more patients, this number is not indicative of the total number of pain management clinics or facilities.
Why target pain management physician groups?
Physicians at pain management practices are at the forefront of managing pain caused by otherwise debilitating conditions, and they rely upon special equipment, technology, and trained staff to properly diagnose, evaluate, treat, prevent, and manage their patient’s health conditions.
Targeting large pain management physician groups can offer significant sales opportunities as physician groups typically present a stable customer base with substantial revenue potential. Additionally, physician groups often centralize purchasing decisions, which can lead to bulk sales and long-term partnerships—the larger the network, the greater the contract.
| Rank | Pain management physician group | State | Definitive ID | # of physicians | Explore dataset |
|---|---|---|---|---|---|
| 1 | National Spine & Pain Centers | MD | 956117 | 138 | Explore |
| 2 | Advanced Pain Care | TX | 630945 | 39 | Explore |
| 3 | Commonwealth Pain & Spine Associates | KY | 603733 | 29 | Explore |
| 4 | Vein Institute & Pain Centers of America (AKA VIP Medical Group) | NY | 948817 | 26 | Explore |
| 5 | Alliance Spine and Pain Centers | GA | 647597 | 26 | Explore |
| 6 | Summit Spine & Joint Centers (FKA Georgia Pain & Wellness Center) | GA | 774962 | 24 | Explore |
| 7 | American Pain Consortium | IN | 634915 | 22 | Explore |
| 8 | Relievus (FKA Advanced Spine & Pain LLC) | NJ | 598166 | 20 | Explore |
| 9 | Advanced Spine and Pain (FKA Pain and Spine Clinics PLLC) | AZ | 927244 | 18 | Explore |
| 10 | Pain Treatment Centers of America | AR | 795825 | 17 | Explore |
| 11 | Precision Spine Care (AKA Charles R Gordon MD PA) | TX | 742947 | 15 | Explore |
| 12 | Southwest Spine & Pain Center (AKA Southwest Spine and Pain Care) | UT | 700542 | 15 | Explore |
| 13 | Pain Specialists of America (FKA Central Texas Pain Center) | TX | 844581 | 14 | Explore |
| 14 | Pain & Spine Institute LLC | IL | 723492 | 13 | Explore |
| 15 | Pain Management Centers of America (FKA Advanced Pain Care Clinic) | KY | 679198 | 13 | Explore |
| 16 | Pain Medicine Associates Inc (AKA Medhat F Mikhael MD Inc) | CA | 717976 | 12 | Explore |
| 17 | Vista Healthcare | UT | 1051753 | 12 | Explore |
| 18 | Advanced Pain Diagnostic & Solutions Inc (FKA Hendrickson & Hunt Pain Management Physicians A Professional Corporate) | CA | 627175 | 11 | Explore |
| 19 | Center for Interventional Pain & Spine | DE | 702485 | 11 | Explore |
| 20 | Jax Spine & Pain Centers | FL | 707570 | 11 | Explore |
Fig. 1 Analysis of data from the Definitive Healthcare PhysicianGroupView product. The number of practices represents only those listed as “active” in our database. Data accessed December 2025.
What is the largest pain management physician group in the U.S.?
National Spine & Pain Centers is the largest pain management physician group in the country based on the number of physicians, with 138 members. This physician group focuses specifically on interventional pain management, which identifies and treats pain using various procedures such as nerve blocks, nerve stimulators, and physical therapy.
Advanced Pain Care is the second largest pain management physician group, with 39 physicians spread across multiple clinics and surgery centers in Texas.
Finally, Commonwealth Pain & Spine Associates is the third largest pain management physician group, with 29 physicians.
Tips for targeting pain management physician groups
Once you’ve curated your target list of pain management physician groups, you can use data and analytical tools to develop insights into your prospects that can guide proposal crafting and improve engagement. Here are some intelligence angles to consider:
Understand their needs
Data such as procedure and claims data, prescription data like most prescribed pain medications, tech install data, and Medicare charges can help you better understand each of your prospects and the unique challenges they face. Using these insights, you can personalize your outreach to those who can see the greatest impact of your product or service.
Highlight relevant benefits
Using your understanding of each physician group’s challenges, highlight the benefits of your product, software, or service that are relevant to their needs. Focus on how your solution can improve patient outcomes, enhance diagnostic capabilities, or optimize operations.
Showcase success stories
Provide evidence of the real-world benefits of your solution. Whether it’s clinical trial data or case studies, select success stories that are most relevant to the needs of the physician group you’re targeting.
Learn more
Healthcare Insights are developed with data and analytics from the Definitive Healthcare platform. Want additional intelligence, including Medicare charges, procedure data, and claims and affiliation insights? Start a free trial now and get access to the latest insights that can help you power a more intelligent sales strategy.
