Top 10 ICD-10 codes for osteoporosis in 2021 

As the U.S. population continues to age, it will become increasingly important for healthcare providers, and the people who deliver drugs, medical devices and other care delivery tools to all understand osteoporosis – what causes it, how it is treated, how it can be prevented and the population demographics of this disease. 

For example, in the U.S., around 10 million people 50 years of age and older have osteoporosis. 

Definitive Healthcare tracks more than 280 ICD-10 codes related to osteoporosis. Below, we rank the top ICD-10 codes for osteoporosis by total diagnoses for 2021.  

Top 10 ICD-10 codes for osteoporosis by total diagnoses in 2021 

Rank 

ICD-10 Code 

ICD-10 Description 

# Total Diagnoses 

% Total Diagnoses 

M810 

Age-related osteoporosis without current pathological fracture 

6,861,904 

74.10% 

Z13820 

Encounter for screening for osteoporosis 

1,334,154 

14.40% 

M818 

Other osteoporosis without current pathological fracture 

411,180 

4.40% 

M8008XA 

Age-related osteoporosis with current pathological fracture, vertebra(e), initial encounter for fracture 

69,651 

0.80% 

M8008XD 

Age-related osteoporosis with current pathological fracture, vertebra(e), subsequent encounter for fracture with routine healing 

65,757 

0.70% 

Z8262 

Family history of osteoporosis 

53,753 

0.60% 

M816 

Localized osteoporosis [Lequesne] 

53,060 

0.60% 

M8000XD 

Age-related osteoporosis with current pathological fracture, unspecified site, subsequent encounter for fracture with routine healing 

51,836 

0.60% 

M8000XA 

Age-related osteoporosis with current pathological fracture, unspecified site, initial encounter for fracture 

47,833 

0.50% 

10 

M80052D 

Age-related osteoporosis with current pathological fracture, left femur, subsequent encounter for fracture with routine healing 

31,000 

0.30% 

Fig 1.Data is from the Definitive Healthcare ClaimsMx product. Data is accurate as of May 2022. 

Which ICD-10 code for osteoporosis had the most diagnoses? 

Code M810, age-related osteoporosis without current pathological fracture, had the most diagnoses with 6,861,904. This code accounted for just over 74% of total osteoporosis diagnoses. Since bone deterioration as a result of the aging process can predispose to osteoporosis, it makes sense that this code topped the list.  

The second code was Z13820, encounter for screening for osteoporosis, with 1,334,154 diagnoses and about 14% of total diagnoses. This ICD-10 code for osteoporosis screening likely had a high number of total diagnoses because physicians recommend osteoporosis screening for all women over age 65

The third code was M818, other osteoporosis without current pathological fracture, with 411,180 diagnoses. This code had a lower percentage of total diagnoses at around 4%. 

Throughout the list, there are both ICD-10 codes for osteoporosis with fracture and osteoporosis without fracture.  

Across the top 10 codes, there was an average of 898,013 diagnoses and a total of 8,980,128 diagnoses, which reflect the prevalence of osteoporosis in the U.S

What is osteoporosis? 

Osteoporosis is a condition that causes bones to become brittle and weak. Specifically, new bone tissue doesn’t replenish fully when the old bone tissue breaks down. Individuals living with osteoporosis are susceptible to bone fractures from various events, such as falls, coughing or bending over.  

While there can be no symptoms in the early stages of osteoporosis, later symptoms of osteoporosis may include: 

  • Stooped posture 
  • Easily broken bones 
  • Back pain 
  • Lost height 

Osteoporosis can affect all populations of people. However, Caucasian and Asian women over age 50 are the most at-risk for osteoporosis. 

How is osteoporosis diagnosed? 

Osteoporosis diagnosis typically involves a bone density scan, or DEXA scan, that uses an X-ray. This bone density test evaluates the proportion of minerals in the bones and outputs a t-score. Zero is a normal t-score, and a negative t-score of around -2.5 indicates osteoporosis. 

What treatment options are there for osteoporosis? 

Osteoporosis treatment mainly involves taking medication and modifying risk factors. Risk factors that may be modified include: 

  • Insufficient exercise 
  • Low body mass 
  • Smoking 
  • Eating disorders  
  • Frequent falls 
  • Alcohol 
  • Vitamin D deficiency  
  • Poor nutrition  

Learn more 

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