Top 20 U.S. hospitals with the most Lyme disease diagnoses

Lyme disease is a common bacterial infection that affects thousands of people across the U.S. According to data from the Definitive Healthcare platform, there were more than 45,000 diagnoses of Lyme disease (ICD-10 code A6920) in 2021.

Below, we’ve ranked the top 20 hospitals by the total number of Lyme disease diagnoses in 2021, using our ClaimsMx product.

Top 20 hospitals ranked by Lyme disease diagnoses in 2021

Hospital Definitive ID State # Total Diagnoses Charges (Primary Diagnosis) Avg Charge/Claim
Wayne Memorial Hospital 3593 PA 1,223 $543,812 $760
Cleveland Clinic Main Campus 3120 OH 746 $157,301 $504
Pen Bay Medical Center 1856 ME 614 $130,172 $376
Northern Light Eastern Maine Medical Center 1862 ME 611 $105,752 $410
Rhode Island Hospital 3603 RI 539 $54,285 $156
Penn Highlands DuBois 3480 PA 485 $102,135 $690
Canton-Potsdam Hospital 2892 NY 461 $83,319 $382
University Hospital 2096 MI 420 $124,647 $535
Wilmington Hospital (AKA Wilmington Health Center) 550103 DE 403 $56,487 $428
Mount Sinai Medical Center (AKA the Mount Sinai Hospital) 2837 NY 398 $96,057 $427
South County Hospital 3611 RI 389 $277,637 $1,192
York Hospital 1874 ME 387 $72,807 $350
Reading Hospital 3454 PA 384 $229,872 $1,321
Stony Brook University Hospital 2915 NY 382 $235,157 $632
Columbia Memorial Hospital 2773 NY 325 $258,817 $1,362
Northern Light Mercy Hospital - State Street Campus (FKA Mercy Hospital - Closed 2022-01-04) 1847 ME 323 $77,711 $361
Meadville Medical Center 3485 PA 309 $120,942 $796
The William W Backus Hospital (AKA Backus Hospital) 738 CT 290 $380,990 $2,268
LincolnHealth - Miles Campus and Hospital (FKA Miles Memorial Hospital) 1858 ME 284 $137,098 $757
Beverly Hospital 1934 MA 278 $126,764 $689

Fig 1. Data is from Definitive Healthcare’s ClaimsMx product. Accessed July 2022.

Which hospital has diagnosed Lyme disease the most?

Wayne Memorial Hospital, located in Pennsylvania, ranks at the top of our list for hospitals with the most Lyme disease diagnoses with a total of 1,223 diagnoses in 2021. Other hospitals on our list include Cleveland Clinic Main Campus in Ohio (746 diagnoses), Pen Bay Medical Center in Maine (614 diagnoses) and Stony Brook University Hospital in New York (382 diagnoses).

All the hospitals featured on our list are located either along the eastern coast of the U.S. or in the Mid-West. It makes sense for these facilities to be diagnosing Lyme disease more often than hospitals elsewhere in the country, as the blacklegged tick is abundantly found in these areas. According to the CDC, the blacklegged tick is the most common carrier of Lyme disease.

What is Lyme disease?

Lyme disease is the most common type of vector-borne disease in the United States. The disease is usually caused by a specific kind of bacteria transmitted to a human during a tick bite. While anyone can be susceptible to a tick bite, people who spend a lot of time outdoors in wooded or grassy areas are at higher risk.

Generally speaking, a tick must be attached to a person for more than 24 hours to spread bacteria.

Lyme disease treatment

Like with many infectious diseases, antibiotics are used to treat Lyme disease. This treatment method helps the human immune system fight against the bacteria that cause the disease.

What happens if Lyme disease goes untreated?

When left untreated, Lyme disease can produce a wide range of symptoms depending on the stage of the infection.

In an article published in the National Center for Biotechnology Information, Lyme disease is divided into three stages. Each stage and common symptoms are described below:

  • Stage 1: This stage may last for 1 – 30 days. Common symptoms include rash, fever, muscle and joint aches and more.
  • Stage 2: This stage may last for 3 – 10 weeks. Flu-like symptoms may be accompanied by disturbances in memory, mood and sleep, pink eye, facial paralysis and more.
  • Stage 3: If Lyme disease is not treated effectively in the first two stages, then it may become chronic. The patient may develop arthritis in one or more joints, and experience skin disorders and other symptoms. At this stage, symptoms may last for months or years.

Which ticks carry Lyme disease?

Not all ticks carry Lyme disease. The CDC reports that the blacklegged tick, also known as the deer tick, is the most common transmitter of the bacteria that causes Lyme disease. However, other species of ticks are known to carry other diseases, such as Rocky Mountain spotted fever, Heartland virus and more.

You can use the CDC’s Tick Bite Data Tracker for information about the frequency of tick bites across every species of tick in your region and to learn more about safely avoiding ticks.

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