Healthcare Insights

Top 20 infectious disease diagnoses

While many organisms live in and on our bodies, they’re often harmless or even helpful. However, under certain conditions, some organisms may cause disease. Some infectious diseases can be passed from person to person, according to the Mayo Clinic.

For this Healthcare Insight, we reviewed data from the Definitive Healthcare ClaimsMx product. The table below shows the most frequent patient visits for infectious and parasitic diseases in 2021.

Top infectious and parasitic diseases based on patient visits in 2021

Rank ICD-10 code ICD-10 description Percent of total infectious and parasitic disease visits Explore dataset
A419 Sepsis, unspecified organism 18.6% Explore
B349 Viral infection, unspecified 12.5% Explore
B351 Tinea unguium 10.3% Explore
B20 Human immunodeficiency virus [HIV] disease 4.2% Explore
B078 Other viral warts 2.4% Explore
A084 Viral intestinal infection, unspecified 2.3% Explore
B029 Zoster without complications 2.2% Explore
B373 Candidiasis of vulva and vagina 2.1% Explore
B070 Plantar wart 2.0% Explore
10 B079 Viral wart, unspecified 1.9% Explore
11 A4189 Other specified sepsis 1.9% Explore
12 B084 Enteroviral vesicular stomatitis with exanthem 1.5% Explore
13 B182 Chronic viral hepatitis C 1.4% Explore
14 B353 Tinea pedis 1.4% Explore
15 A0472 Enterocolitis due to Clostridium difficile, not specified as recurrent 1.2% Explore
16 B354 Tinea corporis 1.2% Explore
17 B370 Candidal stomatitis 1.1% Explore
18 B181 Chronic viral hepatitis B without delta-agent 1.1% Explore
19 B081 Molluscum contagiosum 1.1% Explore
20 B372 Candidiasis of skin and nail 1.0% Explore

Fig. 1 Data is from the Definitive Healthcare ClaimsMx product for calendar year 2021. Claims data is sourced from multiple medical claims clearinghouses in the United States and is updated monthly. Data accessed October 2022.

What is an infectious disease?

Simply put, infectious diseases are disorders caused by pathogenic organisms like bacteria, viruses, fungi, or parasites.

How are infectious diseases contracted?

According to Mayo Clinic, there are several ways to contract an infectious disease:

  • Direct contact: An easy way to catch most infectious diseases is by coming into contact with a person or an animal with the infection.
  • Indirect contact: Many germs can linger on an inanimate object, such as a tabletop, doorknob or faucet handle. When you touch a doorknob handled by someone ill with the flu or a cold, for example, you can pick up the germs left behind.
  • Insect bites: Some germs rely on insect carriers — such as mosquitoes, fleas, lice or ticks — to move from host to host.
  • Food contamination: Disease-causing germs can also infect you through contaminated food and water. This mechanism of transmission allows germs to be spread to many people through a single source.

What are the most common infectious and parasitic diseases?

Sepsis, ICD-10 code A419, accounted for the most patient visits for infectious and parasitic diseases at 18.6% of visits.

Sepsis is also one of the most common healthcare associated infections (HAIs). Incidence of HAIs are tracked by the Centers for Medicare and Medicaid Services (CMS), and hospitals are required to report infections data to the CDC to receive Medicare reimbursements.

Other specific infectious and parasitic diseases that appear on the list include:

Learn more

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