Top 15 lung cancer diagnoses

Lung cancer is among the most common types of cancer in the U.S.

More than 540,000 living Americans had a lung cancer diagnosis during their lives, and there are nearly 237,000 new cases estimated for 2022. Advancements in early detection, additional treatment options, and people quitting smoking are helping to decrease cases.

Patients visit multiple specialists during cancer treatment, including oncologists and radiologists. Each encounter with a healthcare provider includes the patient’s primary diagnosis on the healthcare insurance claim, which results in the number of primary diagnosis claims being greater than the number of patients living with or newly diagnosed with cancer.

Using data from the Definitive Healthcare ClaimsMx product, we analyzed lung cancer ICD-10 codes to find the highest number of primary diagnoses for calendar year 2021.

Most common lung cancer diagnosis codes

Rank ICD-10 Code ICD-10 description Number of primary diagnoses
1 C3490 Malignant neoplasm of unspecified part of unspecified bronchus or lung 679,010
2 C3411 Malignant neoplasm of upper lobe, right bronchus or lung 533,396
3 C3412 Malignant neoplasm of upper lobe, left bronchus or lung 411,835
4 C3491 Malignant neoplasm of unspecified part of right bronchus or lung 284,467
5 C3431 Malignant neoplasm of lower lobe, right bronchus or lung 258,297
6 C3432 Malignant neoplasm of lower lobe, left bronchus or lung 204,748
7 C3492 Malignant neoplasm of unspecified part of left bronchus or lung 197,271
8 C342 Malignant neoplasm of middle lobe, bronchus or lung 75,383
9 C3481 Malignant neoplasm of overlapping sites of right bronchus and lung 53,411
10 C3401 Malignant neoplasm of right main bronchus 42,820
11 C3482 Malignant neoplasm of overlapping sites of left bronchus and lung 29,592
12 C3402 Malignant neoplasm of left main bronchus 28,901
13 C3410 Malignant neoplasm of upper lobe, unspecified bronchus or lung 17,739
14 C3480 Malignant neoplasm of overlapping sites of unspecified bronchus and lung 16,359
15 C3400 Malignant neoplasm of unspecified main bronchus 15,988
16 C3430 Malignant neoplasm of lower lobe, unspecified bronchus or lung 6,775

Fig. 1  Data is from the Definitive Healthcare ClaimsMx product for calendar year 2021. Claims data is sourced from multiple medical claims clearinghouses in the United States and is updated monthly. Data is accurate as of July 2022.

What is the most common lung cancer diagnosis?

ICD-10 C3490 malignant neoplasm of unspecified part of unspecified bronchus or lung had the most primary diagnosis claims at 679,000. Another 533,000 claims were for C3411 malignant neoplasm of upper lobe, right bronchus or lung, and 411,800 claims for C3412 malignant neoplasm of upper lobe, left bronchus or lung.

The 15 codes on this list accounted for more than 2.8 million lung cancer diagnosis claims. They include claims for patients seeing their primary care providers or visiting their oncologist at a cancer center and discussing personalized treatment options.

What are the different kinds of lung cancer?

The two main types of lung cancer are:

Learn more

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