Healthcare Insights
Top medications prescribed by endocrinologists
More than 37 million Americans are estimated to have diabetes and nearly 1.5 million new cases are diagnosed each year. While this chronic condition is often managed through diet, activity, and insulin measurement, endocrinologists play an important role in treating patients with diabetes. Endocrinologists specialize in the regulation of hormones and treatment of glands such as the thyroid and pancreas. Conditions they treat revolve around growth, weight, blood sugar management, and reproductive issues.
For this analysis, we reviewed data from the Definitive Healthcare Atlas Prescription Claims and PhysicianView products for the top 20 most prescribed endocrine medications dispensed to U.S. patients in 2024. We also filtered out non-drug items such as bulk chemicals and medical supplies so as to only show medications.
| Rank | Drug name | % of U.S. endocrinology prescriptions dispensed in 2024 | Explore dataset |
|---|---|---|---|
| 1 | Levothyroxine Sodium | 12.33% | Explore |
| 2 | Ozempic | 5.54% | Explore |
| 3 | Mounjaro | 4.57% | Explore |
| 4 | Synthroid | 3.31% | Explore |
| 5 | Metformin Hcl | 3.29% | Explore |
| 6 | Metformin Hcl Er | 3.19% | Explore |
| 7 | Jardiance | 3.05% | Explore |
| 8 | Atorvastatin Calcium | 2.42% | Explore |
| 9 | Lantus Solostar | 2.40% | Explore |
| 10 | Trulicity | 2.26% | Explore |
| 11 | Methimazole | 1.85% | Explore |
| 12 | Rosuvastatin Calcium | 1.66% | Explore |
| 13 | Vitamin D2 | 1.40% | Explore |
| 14 | Novolog Flexpen | 1.29% | Explore |
| 15 | Farxiga | 1.12% | Explore |
| 16 | Glimepiride | 1.06% | Explore |
| 17 | Novolog | 1.04% | Explore |
| 18 | Liothyronine Sodium | 1.00% | Explore |
| 19 | Lisinopril | 0.96% | Explore |
| 20 | Hydrocortisone | 0.93% | Explore |
Fig. 1 Data is from the Definitive Healthcare Atlas Prescription Claims and PhysicianView products for calendar year 2024. Claims data is sourced from multiple medical claims clearinghouses in the United States and updated monthly. Accessed August 2025.
What are the most common endocrine medications?
With more than 12% share of dispensed endocrine medications, levothyroxine sodium is the most prescribed drug by endocrinologists. The medication is used for hypothyroidism treatment, which is often a co-morbidity of diabetes.
The second most common endocrine medication on the list, Ozempic, is another type 2 diabetes treatment also prescribed as an anti-obesity medication. The drug accounted for 5.54% of dispensed prescriptions in 2024. Ozempic and other GLP-1 drugs have seen mainstream appeal in the consumer market in recent years, disrupting the pharmaceutical industry. Read our analysis on the potential use cases, applications, and risks related to GLP-1 drugs and their impact on the market for more information.
Coming in third place with 4.57% of dispensed prescriptions in 2024 is Mounjaro. Similar to the first two drugs, Mounjaro is commonly prescribed to help treat diabetes patients and weight management.
Learn more
Healthcare Insights are developed with data from the Definitive Healthcare platform. Want even more insights? Check out our analysis on the top prescriptions by cardiologists. Start a free trial now and get access to the latest healthcare intelligence on hospitals, physicians, and other healthcare providers.
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