Top 20 vaccines administered by physicians in 2021
The WHO defines vaccines as “simple, safe, and effective ways of protecting you against harmful diseases, before you come into contact with them.” By introducing small amounts of killed, weakened, or modified forms of pathogens (e.g., viruses and bacteria) the vaccine triggers your immune response and strengthens your body’s natural defenses.
Of course, when thinking about the most administered vaccines in 2021, the new class of mRNA vaccines to help fight the COVID-19 pandemic are at the top the list. In fact, according to Our World in Data, more than 609 million doses of the COVID-19 vaccine were administered just in the United States. However, the COVID-19 vaccines show up at the very bottom of the Top 20 physician-administered vaccines because the vast majority of COVID vaccines were delivered not by physicians, but rather by retail pharmacies, urgent care clinics, school-based vaccine programs, or hospital-administered programs.
Since August was National Immunization Awareness month, we wanted to highlight the top 20 vaccines administered by physicians in 2021, calculated using data from the Definitive Healthcare platform. We used de-identified, all-payor prescription claims data from the Definitive Healthcare ClaimsMx product to highlight the 20 most administered vaccines by physicians for calendar year 2021.
Top 20 vaccines administered by physicians
||Virus / Condition Treated
||IIV4 VACC NO PRSV 0.5 ML IM
||PCV13 VACCINE IM
||TDAP VACCINE 7 YRS/> IM
||Diphtheria, Tetanus, and Whooping Cough
||HEPA VACC PED/ADOL 2 DOSE IM
||Hepatitis A Vaccine for Children
||9VHPV VACCINE 2/3 DOSE IM
||HPV (Human Papillomavirus)
||RV5 VACC 3 DOSE LIVE ORAL
||IIV NO PRSV INCREASED AG IM
||Influenza and Pneumococcal virus
||MENACWYD/MENACWYCRM VACC IM
||DTAP-IPV/HIB VACCINE IM
||Diphtheria, tetanus, pertussis (whooping cough), polio, and Haemophilus influenzae type b
||DTAP-HEP B-IPV VACCINE IM
||Diphtheria, tetanus, pertussis (whooping cough), polio, Haemophilus influenzae type b, hepatitis B
||VAR VACCINE LIVE SUBQ
||Measles, mumps, rubella, and varicella (chickenpox)
||MMR VACCINE SC
||Measles, mumps, and rubella
||HIB PRP-T VACCINE 4 DOSE IM
||HEPB VACC 3 DOSE PED/ADOL IM
||IIV4 VACCINE SPLT 0.5 ML IM
||HZV VACC RECOMBINANT IM
||DTAP VACCINE < 7 YRS IM
||Diphtheria, tetanus, and acellular pertussis
||SARSCOV2 VAC 30MCG/0.3ML IM
||SARSCOV2 VAC 100MCG/0.5ML IM
||CCIIV4 VAC NO PRSV 0.5 ML IM
Fig. 1 Data is from the Definitive Healthcare Claims Mx product for calendar year 2021. Claims data is sourced from multiple medical claims clearinghouses in the United States and is updated monthly. Data is accurate as of August 2022.
What are the most highly administered vaccines?
Based on Definitive Healthcare ClaimsMx data, the most commonly administered vaccine was the flu vaccine, which accounted for 18% of all vaccines administered by physicians 2021. Additional top vaccines on the list protected patients against pneumococcal disease, diphtheria, tetanus, and whooping cough.
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