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Top 5 hospitals in 10 major US cities

Sep 2nd, 2025

By Ethan Popowitz 13 min read
Top 5 hospitals in 10 major US cities

If you’re selling to hospitals, you already know how important it is to do your research on prospects and market changes.

You need to stay on top of a perpetually consolidating and shifting healthcare landscape. With thousands of hospitals and facilities in play, you also need to be able to triage and prioritize your most strategic accounts.

But there is only so much time in the day. How can you make sure you are really targeting the correct hospitals and key stakeholders?

To help you better navigate the healthcare market, here are the top five hospitals, ranked by net patient revenue, for some of the U.S.’ major cities:

Top 5 hospitals in New York, NY

Rank Definitive IDHospital nameNPR# of staffed beds# of dischargesPart of an IDN?Explore dataset
541974 New York-Presbyterian Weill Cornell Medical Center $10,091,059,200  862 139,420 Yes Explore
2843 Tisch Hospital $8,131,192,320  725 110,329 Yes Explore
2846 Memorial Sloan Kettering Cancer Center $5,457,068,544  514 25,648 No Explore
2837 The Mount Sinai Hospital (AKA Mount Sinai Medical Center) $3,634,097,408  1,046 57,509 Yes Explore
2847 Lenox Hill Hospital $1,589,609,088  419 27,966 Yes Explore

Fig. 1 Data from the Definitive Healthcare HospitalView product. Financial and clinical data is from the latest Medicare Cost Report release. Data accessed September 2025.

What hospitals have the highest net patient revenue in New York City?

New York-Presbyterian Hospital/Weill Cornell Medical Center has the highest net patient revenue in New York City, followed by Tisch Hospital. With about $10.1 billion in NPR, it’s also the highest-earning hospital in the country.

Both New York-Presbyterian Hospital/Weill Cornell Medical Center and Tisch Hospital are affiliated with prominent colleges. Cornell University and Columbia University are affiliated with New York-Presbyterian Hospital/Weill Cornell Medical Center while Tisch Hospital is affiliated with NYU School of Medicine.

Many college or university-affiliated hospitals and academic medical centers are actively engaged in cutting-edge research that often includes greater access to innovative procedures and quality care, especially since many college hospitals also serve as teaching and academic hospitals.

Memorial Sloan Kettering Cancer takes the third slot. As one of the top cancer centers in the country, patients from across the state and country seek out care there.

Rounding out the top five are two hospitals from the Mount Sinai Health System—one of the prominent integrated delivery networks (IDNs) in the area. Want more even more insights? Discover the top 25 hospitals in New York.

Explore more New York City hospital lists.

Top 5 hospitals in Los Angeles, CA

Rank Definitive IDHospital nameNet patient revenue# of staffed beds# of dischargesPart of an IDN?Explore dataset
395 Ronald Reagan UCLA Medical Center 2,860,667,648  446 22,739  Yes Explore
476 Los Angeles General Medical Center (FKA LAC & USC Medical Center) 2,051,636,992  564 29,727  Yes Explore
440 Keck Hospital of USC (FKA USC University Hospital) 1,477,065,728  326 11,967  Yes Explore
366 Los Angeles Medical Center 1,400,486,528  492 22,329  Yes Explore
360 Childrens Hospital Los Angeles 1,316,370,816  452 18,094  No Explore

Fig. 2 Data from the Definitive Healthcare HospitalView product. Financial and clinical data is from the latest Medicare Cost Report release. Data accessed September 2025.

What hospitals have the highest net patient revenue in Los Angeles?

Ronald Reagan UCLA Medical Center tops the list for the hospital with the highest net patient revenue in Los Angeles, with an NPR of about $2.9 billion.

Many of the LA hospitals on the list are academic medical centers or teaching hospitals.

Explore more Los Angeles hospitals.

Top 5 hospitals in Chicago, IL

Rank Definitive IDHospital nameNet patient revenue# of staffed beds# of dischargesPart of an IDN?Explore dataset
1135 Northwestern Memorial Hospital 2,596,869,632  944 57,998  Yes Explore
1168 Uchicago Medicine Mitchell Hospital - Hyde Park (AKA Bernard A Mitchell Hospital) 2,593,234,688  737 30,668  Yes Explore
1149 Rush University Medical Center 2,447,251,456  608 27,678  Yes Explore
1142 University of Illinois Hospital 1,226,803,712  401 18,505  Yes Explore
5783 Ann & Robert H Lurie Childrens Hospital of Chicago 1,204,895,872  364 10,952  No Explore

Fig. 3 Data from the Definitive Healthcare HospitalView product. Financial and clinical data is from the latest Medicare Cost Report release. Data accessed September 2025. 

What hospitals have the highest net patient revenue in Chicago?

Northwestern Memorial Hospital and UChicago Medicine Mitchell Hospital top the list, both with an approximate NPR of $2.6 billion. These two facilities, as well as Rush University Medical Center, are designated teaching hospitals and academic medical centers.

Additionally, the Ann & Robert H. Lurie Children’s Hospital of Chicago makes the list, as it is one of the largest and top-ranked pediatric providers in the region. Want a more comprehensive look? Discover the top hospitals in Illinois.

Explore more Chicago hospitals.

Top 5 hospitals in Washington, DC

Rank Definitive IDHospital nameNet patient revenue# of staffed beds# of dischargesPart of an IDN?Explore dataset
754 MedStar Washington Hospital Center 1,633,483,776  719 28,421  Yes Explore
755 Childrens National Hospital 1,435,068,672  323 13,654  Yes Explore
750 MedStar Georgetown University Hospital 1,266,454,912  453 15,160  Yes Explore
748 The George Washington University Hospital 622,912,064  339 17,094  Yes Explore
751 Sibley Memorial Hospital 541,919,168  218 11,423  Yes Explore

Fig. 4 Data from the Definitive Healthcare HospitalView product. Financial and clinical data is from the latest Medicare Cost Report release. Data accessed September 2025. 

What hospitals have the highest net patient revenue in DC?

Two MedStar Health hospitals round out the top three hospitals in the Washington, D.C. area, with MedStar Washington Hospital Center reporting an NPR of $1.6 billion. MedStar Health serves the Washington, D.C. and Baltimore metropolitan area with 10 hospitals, 40 urgent care centers, 31 imaging centers, and 13 ambulatory surgery centers.

Children’s National Hospital takes the second spot on the list and is one of the country’s top-ranked pediatric medical centers.

Discover more Washington D.C. hospital lists.

Top 5 hospitals in San Francisco, CA

Rank Definitive IDHospital nameNet patient revenue# of staffed beds# of dischargesPart of an IDN?Explore dataset
560 UCSF Helen Diller Medical Center 6,146,359,296  887 36,074  Yes Explore
975508 California Pacific Medical Center - Van Ness Campus 1,145,639,296  274 15,180  Yes Explore
975508 California Pacific Medical Center - Van Ness Campus 1,145,639,296  274 15,180  Yes Explore
554 Zuckerberg San Francisco General Hospital (FKA San Francisco General Hospital) 998,937,984  284 14,792  Yes Explore
555 San Francisco Medical Center 838,341,248  239 11,704  Yes Explore

Fig. 5 Data from the Definitive Healthcare HospitalView product. Financial and clinical data is from the latest Medicare Cost Report release. Data accessed September 2025. 

What hospitals have the highest net patient revenue in San Francisco?

UCSF Helen Diller Medical Center has the most reported net patient revenue on our list of San Francisco hospitals, with an NPR of approximately $6.1 billion, outpacing the other four entries on the list.

Uncover more data on hospitals in California.

Top 5 hospitals in Boston, MA

Rank Definitive IDHospital nameNet patient revenue# of staffed beds# of dischargesPart of an IDN?Explore dataset
1973 Massachusetts General Hospital 4,147,126,528  997 46,158  Yes Explore
1978 Dana-Farber Cancer Institute 2,593,981,440  30 1,299  No Explore
1970 Beth Israel Deaconess Medical Center 2,113,445,632  705 38,568  Yes Explore
1979 Boston Childrens Hospital 2,007,910,656  460 15,765  Yes Explore
1976 Boston Medical Center 1,534,908,672  412 22,898  Yes Explore

Fig. 6 Data from the Definitive Healthcare HospitalView product. Financial and clinical data is from the latest Medicare Cost Report release. Data accessed September 2025.

What hospitals have the highest net patient revenue in Boston?

Massachusetts General Hospital Takes the first spot on our list with more than $4.1 billion in NPR. The facility is part of the Mass General Brigham system, one of the top health systems in the Boston area.

Two specialized institutions, the Dana-Faber Cancer Institute and Boston’s Children’s Hospital make an appearance on our list, with a reported NPR of $2.6 billion and $2.0 billion respectively. Looking to take a deeper dive into MA hospitals? Discover the top 20 hospitals in Massachusetts.

Explore more Boston hospital data.

Top 5 hospitals in Philadelphia, PA

Rank Definitive IDHospital nameNet patient revenue# of staffed beds# of dischargesPart of an IDN?Explore dataset
3571 Hospital of the University of Pennsylvania 3,690,950,656  1011 43,429  Yes Explore
3567 Childrens Hospital of Philadelphia (AKA CHOP) 3,075,271,168  692 22,305  Yes Explore
3577 Temple University Hospital 2,220,014,080  761 33,371  Yes Explore
3577 Temple University Hospital 2,220,014,080  451 33,371  Yes Explore
3572 Thomas Jefferson University Hospital 2,092,107,136  866 37,771  Yes Explore

Fig. 7 Data from the Definitive Healthcare HospitalView product. Financial and clinical data is from the latest Medicare Cost Report release. Data accessed September 2025.

What hospitals have the highest net patient revenue in Philadelphia?

The Hospital of the University of Pennsylvania tops the list with nearly $3.7 billion in net patient revenue. Not far behind it is Children’s Hospital of Philadelphia with about $3.1 billion in net patient revenue. Looking for more insights? Discover our list of Pennsylvania’s largest hospitals.

Discover more Philadelphia hospital data.

Top 5 hospitals in Miami, FL

Rank Definitive IDHospital nameNet patient revenue# of staffed beds# of dischargesPart of an IDN?Explore dataset
851 Sylvester Comprehensive Cancer Center 2,712,977,152  538 19,195  Yes Explore
846 Baptist Hospital 2,215,211,520  690 29,721  Yes Explore
845 Jackson Memorial Hospital 1,621,179,776  1595 71,520  Yes Explore
5892 Nicklaus Childrens Hospital (AKA Nicklaus Childrens Health System) 959,783,232  278 10,695  No Explore
852 HCA Florida Kendall Hospital (FKA Kendall Regional Medical Center) 676,215,552  424 22,239  Yes Explore

Fig. 8 Data from the Definitive Healthcare HospitalView product. Financial and clinical data is from the latest Medicare Cost Report release. Data accessed September 2025.

What hospitals have the highest net patient revenue in Miami?

Sylvester Comprehensive Cancer Center generates the highest amount of net patient revenue in Miami, followed by Baptist Hospital and Jackson Memorial Hospital—the latter of which is one of the largest U.S. hospitals by number of staffed beds.

It’s not surprising a cancer center takes the top spot as they are often quite profitable, and this particular hospital hosts a large number of clinical trials and is a hub for cancer research as well. See where Miami’s hospitals fall on our list of the largest hospitals in Florida.

Explore additional Miami hospitals.

Top 5 hospitals in Denver, CO

Rank Definitive IDHospital nameNet patient revenue# of staffed beds# of dischargesPart of an IDN?Explore dataset
663 Denver Health Main Campus 1,292,627,840  387 20,263  Yes Explore
664 HCA HealthONE Presbyterian St Lukes (FKA Presbyterian/St Lukes Medical Center) 634,872,704  311 10,161  Yes Explore
662 Intermountain Health Saint Joseph Hospital (FKA Saint Joseph Hospital) 610,662,080  352 15,746  Yes Explore
661 AdventHealth Porter (FKA Porter Adventist Hospital) 393,363,552  169 6,160  Yes Explore
659 HCA HealthONE Rose (FKA Rose Medical Center) 352,259,168  220 15,609  Yes Explore

Fig. 9 Data from the Definitive Healthcare HospitalView product. Financial and clinical data is from the latest Medicare Cost Report release. Data accessed September 2025.

What hospitals have the highest net patient revenue in Denver?

Denver Health Main Campus comes out far ahead of the other hospitals on the list in the city as its net patient revenue is nearly half a billion more than Presbyterian/St. Luke’s Medical Center in second place.

The majority of healthcare facilities in Denver Health’s system are Federally Qualified Health Centers. Denver Health serves a third of the city’s residents, which likely accounts for its top spot.

Learn how Denver’s hospitals rank on our list of top hospitals in Colorado.

Top 5 hospitals in Dallas, TX

Rank Definitive IDHospital nameNet patient revenue# of staffed beds# of dischargesPart of an IDN?Explore dataset
3923 William P Clements Jr University Hospital (FKA UT Southwestern University Hospital - St Paul) 2,611,149,568  728 33,171  Yes Explore
5377 Childrens Medical Center Dallas 2,030,958,720  406 14,653  Yes Explore
3930 Baylor University Medical Center - Dallas 1,358,351,744  800 36,383  Yes Explore
3914 Medical City Dallas 1,356,415,488  781 34,297  Yes Explore
3931 Parkland Health (FKA Parkland Health and Hospital System) 1,172,520,192  790 49,672  No Explore

Fig. 10 Data from the Definitive Healthcare HospitalView product. Financial and clinical data is from the latest Medicare Cost Report release. Data accessed September 2025.

What hospitals have the highest net patient revenue in Dallas?

The William P. Clements Jr. University Hospital is the top hospital in Dallas, with more than $2.6 billion in net patient revenue. It’s also an academic medical center and teaching hospital affiliated with UT Southwestern Medical School.

Behind that, comes Children’s Medical Center Dallas, another top-ranked pediatric hospital. Children’s Medical Center Dallas is also designated as a Level I Pediatric Trauma Center.

Medical City Dallas, the fourth-place entry in our list, is one of the highest-earning Health Corporation of America hospitals. For more data, discover the largest hospitals in Texas.

Discover how these hospitals compare to other top hospitals in the Dallas-Fort Worth area.

Which type of hospital generates the most revenue in cities?

Based on these rankings, it’s clear that there are a few types of hospitals that generate the highest amount of net patient revenue:

  • Children’s hospitals: The billions of dollars flowing through children’s hospitals every year pay for the care of thousands of children, many of them extremely sick or suffering from chronic conditions requiring a lifetime of treatment. Hospital officials say costs are high because the care is complicated, and the technology is expensive. In addition, the hospitals help fund research into the causes and treatment of diseases.
  • Teaching hospitals: Affiliated with medical schools and associated with high costs, teaching hospitals are the training grounds for the next generation of physicians. The reason for the expense? Not only does Medicare pay teaching hospitals more, to compensate them for their educational mission, but also these hospitals command higher prices in the commercial market due to the medical-school affiliation.
  • Cancer centers: Cancer treatments can be costly due to expensive drugs, cutting-edge treatments, the necessity for experienced doctors with high salaries, and lengthy hospital stays.

Learn more

Want to take a deeper dive into our intelligence on hospitals? Book a demo to see how HospitalView allows you to access deeper insights on more than 9,100 hospitals and IDNs.

Ethan Popowitz

About the Author

Ethan Popowitz

Ethan Popowitz is a Senior Content Writer at Definitive Healthcare. He writes data-driven articles about telehealth, AI, the healthcare staffing shortage, and everything in…

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