Top 50 Hospitals in the U.S.

The following list ranks the top-performing hospitals across the U.S. by net patient revenue (NPR).

Hospitals calculate NPR by subtracting deductions such as charitable donations, bad debt, contractual adjustments from the gross revenue received for all patient care performed.

Top 50 hospitals by net patient revenue

Hospital Name	City	State	Net Patient Revenue	# Of Staffed Beds
NewYork-Presbyterian/Weill Cornell Medical Center	New York	NY	$5,734,047,089	862
Tisch Hospital	New York	NY	$5,674,123,738	725
Cleveland Clinic Main Campus	Cleveland	OH	$5,241,664,591	1,325
Vanderbilt University Medical Center	Nashville	TN	$4,691,813,631	626
UCSF Helen Diller Medical Center at Parnassus Heights	San Francisco	CA	$4,606,030,749	785
University Hospital	Ann Arbor	MI	$4,028,211,053	944
AdventHealth Orlando (FKA Florida Hospital Orlando)	Orlando	FL	$4,003,534,342	2,247
Stanford Hospital	Stanford	CA	$3,976,584,396	523
University of Texas MD Anderson Cancer Center	Houston	TX	$3,672,105,487	710
Cedars-Sinai Medical Center	Los Angeles	CA	$3,550,379,003	882
Memorial Sloan Kettering Cancer Center	New York	NY	$3,417,060,157	514
Emory University Hospital	Atlanta	GA	$3,220,658,079	614
IU Health Methodist Hospital	Indianapolis	IN	$3,113,206,365	1,247
Massachusetts General Hospital	Boston	MA	$2,954,607,780	995
Yale New Haven Hospital	New Haven	CT	$2,923,045,981	581
Mayo Clinic Hospital - Saint Marys Campus	Rochester	MN	$2,837,714,279	1,111
Strong Memorial Hospital	Rochester	NY	$2,702,464,192	761
Montefiore Hospital - Moses Campus	Bronx	NY	$2,695,861,000	1,459
Mount Sinai Medical Center (AKA the Mount Sinai Hospital)	New York	NY	$2,683,766,080	1,087
Duke University Hospital	Durham	NC	$2,675,540,231	960
Orlando Health Orlando Regional Medical Center	Orlando	FL	$2,561,781,315	808
Long Island Jewish Medical Center	New Hyde Park	NY	$2,512,859,641	524
Atrium Health Carolinas Medical Center	Charlotte	NC	$2,485,398,176	1,119
UC San Diego Medical Center - Hillcrest	San Diego	CA	$2,476,193,001	381
Hospital of the University of Pennsylvania	Philadelphia	PA	$2,454,906,000	749
CAMC General Hospital	Charleston	WV	$2,439,389,928	800
University of California Davis Medical Center (AKA UC Davis Medical Center)	Sacramento	CA	$2,412,137,971	598
University of Utah Hospital	Salt Lake City	UT	$2,374,684,466	472
UNC Medical Center (FKA University of North Carolina Hospitals - Memorial Hospital)	Chapel Hill	NC	$2,361,574,427	809
The Johns Hopkins Hospital	Baltimore	MD	$2,353,829,577	1,019
Spectrum Health Butterworth Hospital	Grand Rapids	MI	$2,329,025,938	1,106
University Hospital	Madison	WI	$2,324,088,319	606
The University of Kansas Hospital	Kansas City	KS	$2,296,753,778	854
Brigham and Womens Hospital	Boston	MA	$2,282,609,958	804
Northside Hospital Atlanta	Atlanta	GA	$2,228,962,521	677
Cincinnati Childrens Burnet Campus	Cincinnati	OH	$2,226,690,085	623
UCHealth University of Colorado Hospital	Aurora	CO	$2,226,475,972	653
Ronald Reagan UCLA Medical Center	Los Angeles	CA	$2,201,926,657	446
Ohio State University Wexner Medical Center (AKA Ohio State University Hospital)	Columbus	OH	$2,196,385,250	1,026
Barnes-Jewish Hospital	Saint Louis	MO	$2,146,591,415	1,274
Froedtert Hospital	Milwaukee	WI	$2,123,588,424	676
Houston Methodist Hospital (FKA the Methodist Hospital)	Houston	TX	$2,114,391,175	1,116
University of Iowa Hospitals & Clinics	Iowa City	IA	$2,111,110,331	723
OHSU Hospital - Portland (AKA OHSU Hospital - Marquam Hill Campus)	Portland	OR	$2,095,415,273	549
Lehigh Valley Hospital - Cedar Crest	Allentown	PA	$2,085,604,745	1,061
Childrens Hospital of Philadelphia (AKA CHOP)	Philadelphia	PA	$2,059,747,363	576
Norton Hospital	Louisville	KY	$2,046,532,968	340
Santa Clara Valley Medical Center	San Jose	CA	$2,006,465,085	850
Texas Childrens Hospital	Houston	TX	$1,995,259,698	859
Rush University Medical Center	Chicago	IL	$1,992,372,740	592

Fig 1. Data is from Definitive Healthcare’s Hospitals & IDN database. Data is from the October 2021 Medicare Cost Report release. Data accessed February 2022.

Which hospitals have the highest net patient revenue?

Many hospitals on the list are bringing in billions of dollars in NPR with the top ten reporting over $3.5 billion. Combined, the top 50 hospitals earned more than $141 billion in net patient revenue. The average hospital earned roughly $2.8 billion.

As a key indicator of a healthcare organization’s financial strength, many thought leaders believe increasing NPR to be one of the most difficult challenges hospitals face nationwide. They cite fluctuating patient volumes, decreasing reimbursement rates and constant pressure to keep up with changing regulations as the reasons why improving financial performance is such a struggle. Providers can use healthcare commercial intelligence on payor claims, patient leakage, diagnosis and procedure trends and more to optimize their revenue growth strategy.

Where are the hospitals with the highest NPR located?

The map of the U.S. below indicates where the 50 hospitals with the highest net patient revenues are located.

Hospitals are economic anchors in their communities

The majority of the top 50 hospitals are located along the east coast and the American Mid-West, and all of them serve in or near major cities. High population states like California, Texas, New York and Florida are more likely to have a hospital with high net patient revenue.

Hospitals across the U.S. play a major role in the social and economic health of the communities they serve. According to the Bureau of Labor Statistics, hospitals employ millions of workers, with tens of thousands of new healthcare jobs being added each year. It’s predicted that the healthcare industry will grow faster and add more jobs than any other sector by 2030.

Hospitals can support their communities in more ways than just being a major employer. With high net patient revenue, these organizations can potentially reinvest more funds into new models of care that help improve access to care in rural areas and advance cutting-edge medical research and innovation.

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