Top 50 hospitals in the U.S. by net patient revenue

What hospitals have the highest net patient revenue?

The top U.S. hospital by net patient revenue is New York-Presbyterian Weill Cornell Medical Center with a total net patient revenue of $10.1 billion. Located in the largest city in the U.S., this hospital’s high patient volume is a key source of its higher net patient revenue. In fact, the short-term acute care hospital also ranks highly on our list of hospitals with the highest number of patient discharges.

In second place is Tisch Hospital, also located in New York City, with $8.1 billion in net patient revenue. Like New York-Presbyterian Weill Cornell Medical Center, Tisch Hospital is a voluntary nonprofit facility that sees a high volume of patients.

The third top hospital on our list is Stanford Hospital in Palo Alto, California, with $7.9 billion in net patient revenue.

What types of hospitals have the highest net patient revenue?

Definitive Healthcare tracks nine different hospital types in the HospitalView product:

• Children’s hospitals
• Critical access hospitals
• Department of Defense (DoD) hospitals
• Long-term acute care hospitals
• Psychiatric hospitals
• Rehabilitation hospitals
• Religious non-medical health care institutions
• Short-term acute care hospitals
• VA hospitals

Of the top 50 hospitals listed above, 47 of them are short-term acute care hospitals and three are children’s hospitals. Short-term acute care hospitals are the most prevalent hospital type in the U.S., accounting for more than half of all hospitals. Children’s hospitals also tend to report higher net patient revenue than other types of hospitals due to a greater reliance on commercial insurance over Medicare.

What is the average net patient revenue of hospitals?

In the United States, the average hospital net patient revenue is about $255 million. The average NPR for the top 50 hospitals listed above is $4.2 billion.

The combined net patient revenue of the top 50 hospitals accounts for approximately 14% of the total net patient revenue among hospitals in the U.S.

What makes a hospital profitable?

Many factors play into the profitability of a hospital or health system. Some of the most profitable hospitals in the U.S. likely benefit from factors such as location, health system affiliations, process improvement, and multiple revenue streams.

Hospitals in urban areas, specifically, those that are part of a large health system, are more likely to have higher profit margins and excess revenue.

Additionally, activities beyond patient care, such as investments, retail pharmacy sales, managed care premiums, and reimbursement from quality programs can potentially increase total hospital revenue.

What NPR rankings mean for vendors and investors

Net patient revenue is a key indicator of a hospital’s financial performance and operational scale. Understanding which hospitals generate the highest NPR helps vendors, investors, and providers benchmark competitive positioning, identify partnership opportunities, and assess market concentration.

For vendors and service providers, high-NPR hospitals represent significant commercial opportunities due to their buying power and market influence.

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Healthcare Insights are developed with data from the Definitive Healthcare product portfolio and from CMS. Want even more U.S. hospital lists and healthcare insights? Start a free trial now and get access to the latest intelligence on hospitals, physicians, and other healthcare providers.