Start of Main Content

Healthcare Insights

Top 50 hospitals in the U.S. by net patient revenue

Operating a hospital is expensive. From employee salaries to facility renovation, there are a number of factors that drive high operating expenses. To remain financially stable, hospitals often rely on patient revenue to keep up with such high expenses. Net patient revenue (NPR) is a key financial metric that can be used to grade hospitals’ relative financial strength.

What is net patient revenue for hospitals?

A hospital’s net patient revenue is its aggregate money generated from patient services collected from payors. It is calculated by subtracting patient discounts from total patient revenues.

Using the Definitive Healthcare HospitalView product, we have listed the top 50 hospitals in the U.S. by net patient revenue. The data comes from the Medicare Cost Report and is listed according to the most recent 12-month interval tracked in our product.

Top 50 hospitals in the U.S. by net patient revenue

RankDefinitive IDHospital CityStateNet patient revenueExplore dataset
13556St Luke's University Hospital - BethlehemBethlehemPA$8,944,229,494Explore
2541974NewYork-Presbyterian Weill Cornell Medical CenterNew YorkNY$7,691,623,214Explore
32843Tisch HospitalNew YorkNY$7,240,730,000Explore
4588Stanford Hospital - 300 Pasteur DrStanfordCA$6,761,246,237Explore
53120Cleveland Clinic Main CampusClevelandOH$6,378,833,101Explore
63742Vanderbilt University Medical CenterNashvilleTN$5,441,707,814Explore
7560UCSF Helen Diller Medical Center at Parnassus HeightsSan FranciscoCA$5,436,410,900Explore
8873AdventHealth Orlando (FKA Florida Hospital Orlando)OrlandoFL$5,403,037,761Explore
94017University of Texas MD Anderson Cancer CenterHoustonTX$4,900,378,982Explore
102096University HospitalAnn ArborMI$4,617,071,912Explore
112846Memorial Sloan Kettering Cancer CenterNew YorkNY$4,343,759,944Explore
12430Cedars-Sinai Medical CenterLos AngelesCA$3,922,745,880Explore
131973Massachusetts General HospitalBostonMA$3,879,519,234Explore
14731Yale New Haven HospitalNew HavenCT$3,629,483,033Explore
151365IU Health Methodist HospitalIndianapolisIN$3,577,417,457Explore
162191Mayo Clinic Hospital - Saint Marys CampusRochesterMN$3,445,394,515Explore
17872Orlando Health Orlando Regional Medical CenterOrlandoFL$3,385,817,971Explore
183571Hospital of the University of PennsylvaniaPhiladelphiaPA$3,364,264,152Explore
192818Strong Memorial HospitalRochesterNY$3,314,777,837Explore
20515University of California Davis Medical Center (AKA UC Davis Medical Center)SacramentoCA$3,277,414,909Explore
212663University Hospital (FKA UMDNJ University Hospital)NewarkNJ$3,235,466,972Explore
222837The Mount Sinai Hospital (AKA Mount Sinai Medical Center)New YorkNY$3,200,518,120Explore
232973Duke University HospitalDurhamNC$3,156,628,237Explore
24550UC San Diego Medical CenterSan DiegoCA$3,061,975,842Explore
253003Atrium Health Carolinas Medical CenterCharlotteNC$3,028,966,419Explore
26273024Montefiore Hospital - Moses CampusBronxNY$3,013,724,000Explore
272828Long Island Jewish Medical CenterNew Hyde ParkNY$2,971,774,783Explore
281969Brigham and Womens HospitalBostonMA$2,955,813,891Explore
293015UNC Medical Center (FKA University of North Carolina Hospitals - Memorial Hospital)Chapel HillNC$2,881,592,784Explore
303525Lehigh Valley Hospital - Cedar CrestAllentownPA$2,843,398,596Explore
316386Texas Childrens HospitalHoustonTX$2,842,123,139Explore
321000Northside Hospital AtlantaAtlantaGA$2,794,552,358Explore
334222University of Utah HospitalSalt Lake CityUT$2,716,282,587Explore
343567Childrens Hospital of Philadelphia (AKA CHOP)PhiladelphiaPA$2,695,079,245Explore
354493University HospitalMadisonWI$2,675,255,145Explore
36642UCHealth University of Colorado HospitalAuroraCO$2,661,984,444Explore
374018Memorial Hermann - Texas Medical CenterHoustonTX$2,640,700,669Explore
384012Houston Methodist Hospital (FKA the Methodist Hospital)HoustonTX$2,628,092,977Explore
39395Ronald Reagan UCLA Medical CenterLos AngelesCA$2,620,570,310Explore
403623Medical University of South Carolina Medical CenterCharlestonSC$2,609,674,387Explore
411678Norton HospitalLouisvilleKY$2,589,779,490Explore
421631The University of Kansas HospitalKansas CityKS$2,584,926,398Explore
432035Corewell Health Butterworth Hospital (FKA Spectrum Health Butterworth Hospital)Grand RapidsMI$2,573,776,653Explore
443421OHSU Hospital - Portland (AKA OHSU Hospital - Marquam Hill Campus)PortlandOR$2,570,683,962Explore
45596Santa Clara Valley Medical CenterSan JoseCA$2,551,664,419Explore
4671UAB HospitalBirminghamAL$2,534,353,450Explore
475576Cincinnati Childrens Burnet CampusCincinnatiOH$2,508,408,288Explore
481914The Johns Hopkins HospitalBaltimoreMD$2,465,608,109Explore
492442Barnes-Jewish HospitalSaint LouisMO$2,418,252,342Explore
503862Methodist HospitalSan AntonioTX$2,417,272,580Explore

Fig. 1 Data is from the Definitive Healthcare HospitalView product. Data is from the Medicare Cost Report and is displayed according to the most recent 12-month interval tracked in our database. Data accessed May 2024.

What hospitals have the highest net patient revenue?

The top U.S. hospital by net patient revenue is St. Luke’s University Hospital – Bethlehem in Bethlehem, Pennsylvania with a total revenue of $8.9 billion. As the headquarters of the nonprofit St. Luke’s University Health Network, the University Hospital in Bethlehem is one of 15 campuses and over 300 outpatient sites in the network.

In second place for largest U.S. hospitals by NPR is New York-Presbyterian Weill Cornell Medical Center with $7.6 billion. Located in the largest city in the U.S., this hospital’s high patient volume is a key source of its higher net patient revenue. In fact, New York-Presbyterian Weill Cornell Medical Center also takes second place on the list of hospitals with the highest number of patient discharges.

The third top hospital by NPR is Tisch Hospital, also located in New York City, with $7.2 billion. Like New York-Presbyterian Weill Cornell Medical Center, Tisch Hospital also sees a high volume of patients. This hospital also makes the list of top hospitals with the highest number of patient discharges.

What types of hospitals have the highest net patient revenue?

Definitive Healthcare tracks nine different hospital types in the HospitalView product:

Of the top 50 hospitals listed above, 47 of them are short-term acute care hospitals and three are children’s hospitals.

Short-term acute care hospitals are the most prevalent hospital type in the U.S., accounting for more than half of all hospitals.

What is the average net patient revenue of hospitals?

In the United States, the average hospital net patient revenue is $224.9 million. The average NPR for the top 50 hospitals listed above is $3.6 billion.

The combined net patient revenue of the top 50 hospitals accounts for 13.7% of all nationwide hospital NPR.

What makes a hospital profitable?

Many factors play into the profitability of a hospital or health system. Some of the richest hospitals in the U.S. likely benefit from factors such as location, health system affiliations, process improvement, and multiple revenue streams.

Hospitals in urban areas, specifically those that are part of a large health system, are more likely to have higher profit margins and excess revenue.

Additionally, activities beyond patient care, such as investments, retail pharmacy sales, managed care premiums, and reimbursement from quality programs can potentially increase total hospital revenue.

How many of the top hospitals by NPR are part of a health system?

Of the factors that influence the profitability of a hospital, being part of a larger health system is very prevalent in this list of top 50 hospitals by NPR. Among the top hospitals listed above, 48 are part of a health system.

While the majority of them do not belong to the top health systems by net patient revenue, having health system affiliation alone can increase the likelihood of having more affiliated facilities, potentially driving access to more patients and higher net patient revenue.

Interestingly, Methodist Hospital in San Antonio—the 50th and final hospital on our list—is the only hospital listed that belongs to HCA Healthcare, the highest-earning and largest IDN in the U.S.

Learn more

Healthcare Insights are developed with healthcare commercial intelligence from the Definitive Healthcare platform. Want even more insights? Start a free trial now and get access to the latest healthcare commercial intelligence on hospitals, physicians, and other healthcare providers.